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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Harmine, Temozolomide
Phytochemical Name Harmine (PubChem CID: 5280953 )
Anticancer drug Name Temozolomide (PubChem CID: 5394 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 7
Pair Name Harmine, Temozolomide
Disease Info [ICD-11: 2A00] Glioblastoma multiforme Investigative
Gene Regulation Down-regulation Expression MMP2 hsa4313
Down-regulation Expression MMP9 hsa4318
In Vitro Model T98G Glioblastoma Homo sapiens (Human) CVCL_0556
Result Harmine Augments the Cytotoxic and Anti-invasive Potential of Temozolomide Against Glioblastoma Multiforme Cells
03. Reference
No. Title Href
1 Harmine Augments the Cytotoxic and Anti-invasive Potential of Temozolomide Against Glioblastoma Multiforme Cells. Jundishapur J Nat Pharm Prod. 2021. doi:10.5812/jjnpp.115464. Click
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